CNBC is excited to announce that nominations are now open for the 2024 Disruptor 50 list, the annual recognition of the most innovative venture-backed companies. These companies are using breakthrough technology to tackle the growing economic and consumer challenges of today. With the deadline for submissions on Friday, Feb. 16 at 11:59 pm EST, the race is on to uncover the next wave of disruptors.

Despite the significant potential for the companies named on last year’s Disruptor 50 list, they continue to face challenges as we move towards 2024. One major obstacle is the impact of high interest rates, which has led to a tightening of the supply of venture capital. This tightening has also resulted in a mostly closed IPO window for venture-backed startups for the second consecutive year.

A notable past Disruptor 50 company, Instacart, embarked on its journey to the public market this year but failed to maintain its initial public offering (IPO) pricing. This highlights the difficulties faced by even the most promising disruptors in the current market environment.

The third quarter of the previous year recorded the lowest number of venture deals in the last six years, according to PitchBook. Furthermore, U.S. venture capital fundraising is projected to hit a nine-year low in 2023, which poses additional challenges for aspiring disruptors seeking crucial financial support.

In the face of these challenges, many companies are forced to raise funds at reduced valuations, commonly referred to as “down rounds.” In fact, the number of down rounds has reached a ten-year high, with over a quarter of fundraising rounds completed in the previous year happening at a flat or reduced valuation. This trend emphasizes the difficulties companies face in securing adequate funding.

Tragically, some previously high-flying and high-profile Disruptor 50 companies have experienced significant setbacks. The examples of Convoy and WeWork stand as reminders of the risks involved in the disruptive business landscape. These failures serve as a warning to new startups about the importance of sustainable growth and adaptability.

Despite the challenging funding environment, the entrepreneurial spirit seems unbroken, as business formation is predicted to set a new record in 2023. This surge in new ventures emerges from the wake of the Covid-19 pandemic, demonstrating the resilience and determination of entrepreneurs.

Notably, a significant number of new companies emerging in the disruptive landscape are involved in the booming artificial intelligence (AI) sector. The hype cycle sparked by OpenAI, the top Disruptor 50 company of 2023, continues to inspire entrepreneurs to innovate in this field. Additionally, the biotech sector attracts robust investment in the midst of the tighter venture capital climate, underscoring the potential for breakthroughs in this area.

Nominees for the 2024 Disruptor 50 list will undergo a comprehensive and rigorous evaluation process. This process entails extensive research and scoring across a wide range of quantitative and qualitative criteria. Factors considered include scalability, revenue and user growth, and the effective use of breakthrough technology. Workforce diversity is also a crucial element in the assessment process.

To ensure a fair evaluation, an advisory board composed of industry leaders in innovation and entrepreneurship will provide input on the quantitative aspects of the evaluation. Meanwhile, a team of CNBC editorial staff will closely review all submissions, providing insightful qualitative assessments for each nominee. This rigorous evaluation process guarantees that only the most deserving companies will earn a spot on the highly anticipated 2024 Disruptor 50 list.

The 2024 Disruptor 50 list promises to uncover and celebrate the most groundbreaking companies in the current disruptive landscape. While the challenges in the venture capital landscape are significant, the resilience and determination of entrepreneurs continue to drive new business formation. With a spotlight on breakthrough technologies and innovative solutions, the list will showcase the companies that are shaping the future. Stay tuned for the announcement of the 2024 honorees in April, with the release of the list on CNBC’s TV and digital platforms in May.

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